Canine Red Blood Cells

Leukocytes present are minimally distorted.

Canine red blood cells.

Some dog breeds have inherited macrothrombocytes e g. The whole blood is washed to remove the platelet rich plasma buffy coat layer and leukocytes. Canine red blood cells are biconcave discs with fairly deep central indentation and therefore when spread on a slide have quite noticeable central pallor. A low red blood cell count can be the result of blood loss the destruction of the red blood cells or an inadequate production of new red blood cells.

Dog red blood cells are quite uniform in size and platelets are usually uniform in size with some large platelets being seen the arrows point to two platelets of markedly different sizes in blood from a healthy dog. In severe blood loss anemia red blood cells are lost but death usually results from the loss of total blood volume rather than from the lack of oxygen caused by loss of red blood cells. Reasons for transfusion included hemorrhage n 222 hemolysis n 43 and ineffectiv. Canine red blood cells from innovative research are manufactured using whole blood collections from dogs located in the united states.

Hemolysis may be caused by toxins infections abnormalities present at birth drugs or antibodies that attack the red blood cells. If your dog has anemia there s been a drop in the number of his red blood cells. Red blood cells are perishable and are collected and processed upon receipt of order. Low magnification canine blood film 200 wright giemsa stain illustrating the counting area of the slide which contains red blood cells rbcs in a monolayer with minimal overlap.

Compare canine red blood cells from leading suppliers on biocompare. View specifications prices citations reviews and more. Echinocytes or crenated red blood cells in contrast have shorter usually sharp blunt spicules of uniform length which are more evenly spaced around their periphery. In dogs the most common cause of serious hemolysis is an antibody directed against that dog s own red blood cells immune mediated hemolytic anemia.

Feline erythrocytes are smaller approximately 6 µm in diameter and more cup shaped so they lack the prominent central pallor seen in canine rbcs. In some species those with smaller red blood cells such as horses and cats echinocytes may have blunt ends. The image is taken at 200 instead of 100 due to distortion caused by the microscope imaging program a. Canine red blood cell transfusion practice red blood cell rbc transfusions in 307 dogs were reviewed.

White blood cells wbcs can become distorted and. Canine red blood cells rbcs are approximately 7 micrometers µm in diameter and shaped like biconcave discs with prominent central pallor. The mean ptv of canine red blood cells stored in nutricel for 35 days was 85 with 51cr and 90 with 99mtc 51cr. Canine blood film at the feathered edge of the slide is too distorted to easily evaluate cell morphology.

A total of 658 units of rbcs including 474 72 units of packed red blood cells prbcs and 184 28 units of whole blood wb were administered.